Cosmological large-scale structure analyses based on two-point correlation functions often assume a Gaussian likelihood function with a fixed covariance matrix.We study the impact on cosmological parameter estimation of ignoring the parameter dependence of this covariance matrix, focusing on the particular case of joint weak-lensing and southwester
The accumulation of poorly differentiated cells is a hallmark of breast neoplasia and progression.Thus an understanding of the factors controlling mammary differentiation is critical to a proper understanding of breast tumourigenesis.The Inhibitor of Differentiation 1 (Id1) protein has well documented roles in the control of mammary epithelial sout
Abstract Background Accurate identification of real somatic variants is a primary part of cancer genome studies and precision oncology.However, artifacts introduced in various steps of sequencing obfuscate confidence in variant calling.Current computational approaches to variant filtering involve intensive interrogation of Binary Alignment Map (BAM
Abstract Background Euphorbia lathyris L., a Traditional Chinese medicine (TCM), is commonly used for the treatment of hydropsy, ascites, constipation, amenorrhea, and scabies.Semen Euphorbiae Pulveratum, which is another type of Euphorbia lathyris that is commonly used in TCM practice and is obtained by removing the oil from the seed that is calle
Gitte S Jensen,1 Bijal Shah,2 Robert Holtz,3 Ashok Patel,4 Donald C Lo2 1NIS Labs, Klamath Falls, OR, 2Department of Neurobiology, Center for Drug Discovery, Duke University Medical Center, Durham, NC, 3BioInnovation Laboratories, Inc., Lakewood, CO, 4Centre Manufacturing LLC, Eden Prairie, MN, USA Objective: The aim of this study was to evaluate t